Okay, so not joking:

I think Trump can beat Zuck, and I think the Democrats (or rather the party leadership) are currently, uh, clueless enough to pick him.  I don’t think the rank’n’files want him.

I do think he’s positioning himself to run.  It’s going to be an uphill battle seeing as he’s a white male tech billionaire, and not even a cool one like Elon Musk.

Trump’s going to be tougher to beat than he looks.  It depends in part of how much legislation he can get passed and how much of the GOP elite he can shift - particularly during the mid-terms.  The Trump base want to use the mid-terms for that purpose.

By the time we get to 2022, I think some of the Democratic leadership will have changed, and conditions will be less favorable for The Zuck.

I put 70% Zuck goes for it, 30% he gets the nomination if he does, and 30% he gets the Presidency if he gets the nomination, for about ~6% chance.